Hopes rise on coronavirus drug remdesivir

www.nature.com /articles/d41586-020-01295-8
Heidi Ledford
7-8 minutes
A patient at the intensive care unit receives treatment from two hospital workers in Hefei, China

Coronavirus causes severe respiratory illness in some people.Credit: Zhang Yazi/China News Service via Getty

An experimental drug — and one of the world’s best hopes against COVID-19 — could shorten the time to recovery from coronavirus infection, according to the largest and most rigorous clinical trial of the compound.

The experimental drug, called remdesivir, interferes with replication of some viruses, including the SARS-CoV-2 virus responsible for the current pandemic. On 29 April, Anthony Fauci, director of the US National Institute of Allergy and Infectious Disease (NIAID), announced that a clinical trial of more than a thousand people showed that people taking remdesivir recovered in 11 days on average, compared to 15 days for those on a placebo.

The COVID-19 vaccine development landscape

Stephen Mayhew
10-13 minutes
 (Figures and Tables ommited, for full article go here)
The genetic sequence of SARS-CoV-2, the coronavirus that causes COVID-19, was published on 11 January 2020, triggering intense global R&D activity to develop a vaccine against the disease. The scale of the humanitarian and economic impact of the COVID-19 pandemic is driving evaluation of next-generation vaccine technology platforms through novel paradigms to accelerate development, and the first COVID-19 vaccine candidate entered human clinical testing with unprecedented rapidity on 16 March 2020.

Powerful antibiotics discovered using AI

Jo Marchant
5-6 minutes
https://www.nature.com/articles/d41586-020-00018-3
Coloured scanning electron micrograph (SEM) of Escherichia coli bacteria (green) taken from the small intestine of a child.

Escherichia coli bacteria, coloured green, in a scanning electron micrograph.Credit: Stephanie Schuller/SPL

A pioneering machine-learning approach has identified powerful new types of antibiotic from a pool of more than 100 million molecules — including one that works against a wide range of bacteria, including tuberculosis and strains considered untreatable.

'Brexit' May Hurt Britain Where It Thrives: Science and Research

By KIMIKO DE FREYTAS-TAMURA
OCT. 17, 2016

The New York Times

LONDON — When Adam Durant started his company analyzing climate-related threats to aircraft, he and his team of researchers symbolized the possibilities offered by the European Union.

Soon after graduating from college, Mr. Durant received a prestigious European Union grant to study atmospheric chemistry and conduct climate-related research. When he started his business, he hired staff members from Belgium and France without having to sponsor their visas.

But since Britain voted in June to leave the bloc, Mr. Durant has become the archetype of something very different: a nervous entrepreneur, unsure about future funding and even considering leaving the country.

Landsat 8 to the rescue

NASA prepares to launch satellite that will continue historic record of global change.

NATURE

Jeff Tollefson

06 February 2013

When Landsat 5 fell silent on 6 January, scientists across the globe mourned its passing but gave thanks for its fortitude. The satellite had lasted a record-breaking 28 years, snapping images of the changing planet from melting glaciers to burning rainforests, while its successors faltered. Landsat 6 failed during launch and Landsat 7, at 13 years old, is partially blind and has limited fuel. With the passing of Landsat 5, the future of the world’s longest-running — and perhaps most influential — set of data on global change rests with Landsat 8, which is scheduled to launch next week from Vandenberg Air Force Base in California.

Greek science on the brink

Financial woes spur controversial reforms of the country's research system.

Nature

Alison Abbott

11 January 2012

Nature

 

481,

 

123–124

 

(12 January 2012)

 

doi:10.1038/481123a

… Just a handful of Greece's universities and research institutions are internationally competitive…

… The rectors of Greece's 24 public universities, for their part, seem appalled by the law…

… It is shocking that academic leaders would show no respect for a law…

… Greece does not have a dedicated research funding agency…